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Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages

BACKGROUND: KRAS mutation occurs in 35%-40% of colorectal cancer (CRC). The aim of our study was to evaluate the pathological and molecular features of specific KRAS mutated colorectal carcinomas. KRAS and BRAF(V600E) mutation tests were performed in 762 primary tumors from a consecutive cohort stud...

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Detalles Bibliográficos
Autores principales:	Li, Wenbin, Qiu, Tian, Zhi, Wenxue, Shi, Susheng, Zou, Shuangmei, Ling, Yun, Shan, Ling, Ying, Jianming, Lu, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423107/ https://www.ncbi.nlm.nih.gov/pubmed/25929517 http://dx.doi.org/10.1186/s12885-015-1345-3

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