HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells

BACKGROUND: Myeloid cells are key players in the recognition and response of the host against invading viruses. Paradoxically, upon HIV-1 infection, myeloid cells might also promote viral pathogenesis through trans-infection, a mechanism that promotes HIV-1 transmission to target cells via viral cap...

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Detalles Bibliográficos
Autores principales: Pino, Maria, Erkizia, Itziar, Benet, Susana, Erikson, Elina, Fernández-Figueras, Maria Teresa, Guerrero, Dolores, Dalmau, Judith, Ouchi, Dan, Rausell, Antonio, Ciuffi, Angela, Keppler, Oliver T, Telenti, Amalio, Kräusslich, Hans-Georg, Martinez-Picado, Javier, Izquierdo-Useros, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423124/
https://www.ncbi.nlm.nih.gov/pubmed/25947229
http://dx.doi.org/10.1186/s12977-015-0160-x

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