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Do Cinnamon Supplements Cause Acute Hepatitis?

Patient: Female, 73 Final Diagnosis: Drug induced acute hepatitis Symptoms: Abdominal pain • diarrhea • vomiting Medication: — Clinical Procedure: — Specialty: Gastroenterology and Hepatology OBJECTIVE: Unusual or unexpected effect of treatment BACKGROUND: The use of herbal medications to treat vari...

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Autores principales: Brancheau, Daniel, Patel, Brijesh, Zughaib, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423171/
https://www.ncbi.nlm.nih.gov/pubmed/25923145
http://dx.doi.org/10.12659/AJCR.892804
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author Brancheau, Daniel
Patel, Brijesh
Zughaib, Marcel
author_facet Brancheau, Daniel
Patel, Brijesh
Zughaib, Marcel
author_sort Brancheau, Daniel
collection PubMed
description Patient: Female, 73 Final Diagnosis: Drug induced acute hepatitis Symptoms: Abdominal pain • diarrhea • vomiting Medication: — Clinical Procedure: — Specialty: Gastroenterology and Hepatology OBJECTIVE: Unusual or unexpected effect of treatment BACKGROUND: The use of herbal medications to treat various diseases is on the rise. Cinnamon has been reported to improve glycolated hemoglobin and serum glucose levels. When patients consider the benefit of such substances, they are often not aware of potential adverse effects and drug interactions. Cinnamon, via coumarin, can cause liver toxicity. Therefore, its concomitant use with hepatotoxic drugs should be avoided. CASE REPORT: A 73-year-old woman was seen in the Emergency Department complaining of abdominal pain associated with vomiting and diarrhea after she started taking cinnamon supplements for about 1 week. The patient had been taking statin for coronary artery disease for many months. The laboratory workup and imaging studies confirmed the diagnosis of hepatitis. The detail workup did not reveal any specific cause. Cinnamon and statin were held. A few weeks after discharge, the statin was resumed without any further complications. This led to a diagnosis of cinnamon-statin combination-induced hepatitis. CONCLUSIONS: A combination of cinnamon supplement and statin can cause hepatitis, and it should be discouraged.
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spelling pubmed-44231712015-05-13 Do Cinnamon Supplements Cause Acute Hepatitis? Brancheau, Daniel Patel, Brijesh Zughaib, Marcel Am J Case Rep Articles Patient: Female, 73 Final Diagnosis: Drug induced acute hepatitis Symptoms: Abdominal pain • diarrhea • vomiting Medication: — Clinical Procedure: — Specialty: Gastroenterology and Hepatology OBJECTIVE: Unusual or unexpected effect of treatment BACKGROUND: The use of herbal medications to treat various diseases is on the rise. Cinnamon has been reported to improve glycolated hemoglobin and serum glucose levels. When patients consider the benefit of such substances, they are often not aware of potential adverse effects and drug interactions. Cinnamon, via coumarin, can cause liver toxicity. Therefore, its concomitant use with hepatotoxic drugs should be avoided. CASE REPORT: A 73-year-old woman was seen in the Emergency Department complaining of abdominal pain associated with vomiting and diarrhea after she started taking cinnamon supplements for about 1 week. The patient had been taking statin for coronary artery disease for many months. The laboratory workup and imaging studies confirmed the diagnosis of hepatitis. The detail workup did not reveal any specific cause. Cinnamon and statin were held. A few weeks after discharge, the statin was resumed without any further complications. This led to a diagnosis of cinnamon-statin combination-induced hepatitis. CONCLUSIONS: A combination of cinnamon supplement and statin can cause hepatitis, and it should be discouraged. International Scientific Literature, Inc. 2015-04-29 /pmc/articles/PMC4423171/ /pubmed/25923145 http://dx.doi.org/10.12659/AJCR.892804 Text en © Am J Case Rep, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Articles
Brancheau, Daniel
Patel, Brijesh
Zughaib, Marcel
Do Cinnamon Supplements Cause Acute Hepatitis?
title Do Cinnamon Supplements Cause Acute Hepatitis?
title_full Do Cinnamon Supplements Cause Acute Hepatitis?
title_fullStr Do Cinnamon Supplements Cause Acute Hepatitis?
title_full_unstemmed Do Cinnamon Supplements Cause Acute Hepatitis?
title_short Do Cinnamon Supplements Cause Acute Hepatitis?
title_sort do cinnamon supplements cause acute hepatitis?
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423171/
https://www.ncbi.nlm.nih.gov/pubmed/25923145
http://dx.doi.org/10.12659/AJCR.892804
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