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Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Un...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423172/ https://www.ncbi.nlm.nih.gov/pubmed/25907152 http://dx.doi.org/10.12659/AJCR.892546 |
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author | Manca, Sandra Fois, Alessandro Giuseppe Santoru, Luigi Trisolini, Rocco Polo, Maria Francesca Ostera, Salvatore Patelli, Marco Pirina, Pietro |
author_facet | Manca, Sandra Fois, Alessandro Giuseppe Santoru, Luigi Trisolini, Rocco Polo, Maria Francesca Ostera, Salvatore Patelli, Marco Pirina, Pietro |
author_sort | Manca, Sandra |
collection | PubMed |
description | Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Unusual clinical course BACKGROUND: Pulmonary tuberculosis (TB), a highly contagious infectious disease, is a significant public health problem all over the world and remains an important cause of preventable death in the adult population. Endobronchial TB is an unusual form of thoracic TB that may be complicated by tracheobronchial stenosis, and bronchoesophageal fistula formation is a very rare complication. Tubercular lymphadenitis can also lead to fistula formation through a process of caseum necrosis and opening of a fistula between the bronchus and oesophagus. CASE REPORT: We report an uncommon case of thoracic TB in an immunocompetent 73-year-old Caucasian man who presented several problems: bronchoesophageal fistula, endobronchial TB, and mediastinal lymphadenopathy in the absence of contemporary parenchymal consolidation. Furthermore, he presented a normal chest radiograph and mostly unclear and non-specific symptoms at onset. CONCLUSIONS: We emphasize the need for a better knowledge of this illness and awareness that it may have an unusual presentation. In these cases, diagnosis and proper treatment can be delayed, with severe complications for the patient. Pulmonary TB remains a real diagnostic challenge: a normal chest radiograph and nonspecific symptoms do not allow us to exclude this persistent infectious disease. |
format | Online Article Text |
id | pubmed-4423172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44231722015-05-13 Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness Manca, Sandra Fois, Alessandro Giuseppe Santoru, Luigi Trisolini, Rocco Polo, Maria Francesca Ostera, Salvatore Patelli, Marco Pirina, Pietro Am J Case Rep Articles Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Unusual clinical course BACKGROUND: Pulmonary tuberculosis (TB), a highly contagious infectious disease, is a significant public health problem all over the world and remains an important cause of preventable death in the adult population. Endobronchial TB is an unusual form of thoracic TB that may be complicated by tracheobronchial stenosis, and bronchoesophageal fistula formation is a very rare complication. Tubercular lymphadenitis can also lead to fistula formation through a process of caseum necrosis and opening of a fistula between the bronchus and oesophagus. CASE REPORT: We report an uncommon case of thoracic TB in an immunocompetent 73-year-old Caucasian man who presented several problems: bronchoesophageal fistula, endobronchial TB, and mediastinal lymphadenopathy in the absence of contemporary parenchymal consolidation. Furthermore, he presented a normal chest radiograph and mostly unclear and non-specific symptoms at onset. CONCLUSIONS: We emphasize the need for a better knowledge of this illness and awareness that it may have an unusual presentation. In these cases, diagnosis and proper treatment can be delayed, with severe complications for the patient. Pulmonary TB remains a real diagnostic challenge: a normal chest radiograph and nonspecific symptoms do not allow us to exclude this persistent infectious disease. International Scientific Literature, Inc. 2015-04-24 /pmc/articles/PMC4423172/ /pubmed/25907152 http://dx.doi.org/10.12659/AJCR.892546 Text en © Am J Case Rep, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License |
spellingShingle | Articles Manca, Sandra Fois, Alessandro Giuseppe Santoru, Luigi Trisolini, Rocco Polo, Maria Francesca Ostera, Salvatore Patelli, Marco Pirina, Pietro Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title | Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title_full | Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title_fullStr | Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title_full_unstemmed | Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title_short | Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness |
title_sort | unusual clinical presentation of thoracic tuberculosis: the need for a better knowledge of illness |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423172/ https://www.ncbi.nlm.nih.gov/pubmed/25907152 http://dx.doi.org/10.12659/AJCR.892546 |
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