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Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness

Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Un...

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Autores principales: Manca, Sandra, Fois, Alessandro Giuseppe, Santoru, Luigi, Trisolini, Rocco, Polo, Maria Francesca, Ostera, Salvatore, Patelli, Marco, Pirina, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423172/
https://www.ncbi.nlm.nih.gov/pubmed/25907152
http://dx.doi.org/10.12659/AJCR.892546
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author Manca, Sandra
Fois, Alessandro Giuseppe
Santoru, Luigi
Trisolini, Rocco
Polo, Maria Francesca
Ostera, Salvatore
Patelli, Marco
Pirina, Pietro
author_facet Manca, Sandra
Fois, Alessandro Giuseppe
Santoru, Luigi
Trisolini, Rocco
Polo, Maria Francesca
Ostera, Salvatore
Patelli, Marco
Pirina, Pietro
author_sort Manca, Sandra
collection PubMed
description Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Unusual clinical course BACKGROUND: Pulmonary tuberculosis (TB), a highly contagious infectious disease, is a significant public health problem all over the world and remains an important cause of preventable death in the adult population. Endobronchial TB is an unusual form of thoracic TB that may be complicated by tracheobronchial stenosis, and bronchoesophageal fistula formation is a very rare complication. Tubercular lymphadenitis can also lead to fistula formation through a process of caseum necrosis and opening of a fistula between the bronchus and oesophagus. CASE REPORT: We report an uncommon case of thoracic TB in an immunocompetent 73-year-old Caucasian man who presented several problems: bronchoesophageal fistula, endobronchial TB, and mediastinal lymphadenopathy in the absence of contemporary parenchymal consolidation. Furthermore, he presented a normal chest radiograph and mostly unclear and non-specific symptoms at onset. CONCLUSIONS: We emphasize the need for a better knowledge of this illness and awareness that it may have an unusual presentation. In these cases, diagnosis and proper treatment can be delayed, with severe complications for the patient. Pulmonary TB remains a real diagnostic challenge: a normal chest radiograph and nonspecific symptoms do not allow us to exclude this persistent infectious disease.
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spelling pubmed-44231722015-05-13 Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness Manca, Sandra Fois, Alessandro Giuseppe Santoru, Luigi Trisolini, Rocco Polo, Maria Francesca Ostera, Salvatore Patelli, Marco Pirina, Pietro Am J Case Rep Articles Patient: Male, 73 Final Diagnosis: Bronchoesophageal fistula in endobronchial tuberculosis and mediastinal lymphadenopathy Symptoms: Nonproductive cough • weight loss Medication: Isoniazid • rifampin • pyrazinamide • ethambutol Clinical Procedure: Laser treatment Specialty: Pulmonology OBJECTIVE: Unusual clinical course BACKGROUND: Pulmonary tuberculosis (TB), a highly contagious infectious disease, is a significant public health problem all over the world and remains an important cause of preventable death in the adult population. Endobronchial TB is an unusual form of thoracic TB that may be complicated by tracheobronchial stenosis, and bronchoesophageal fistula formation is a very rare complication. Tubercular lymphadenitis can also lead to fistula formation through a process of caseum necrosis and opening of a fistula between the bronchus and oesophagus. CASE REPORT: We report an uncommon case of thoracic TB in an immunocompetent 73-year-old Caucasian man who presented several problems: bronchoesophageal fistula, endobronchial TB, and mediastinal lymphadenopathy in the absence of contemporary parenchymal consolidation. Furthermore, he presented a normal chest radiograph and mostly unclear and non-specific symptoms at onset. CONCLUSIONS: We emphasize the need for a better knowledge of this illness and awareness that it may have an unusual presentation. In these cases, diagnosis and proper treatment can be delayed, with severe complications for the patient. Pulmonary TB remains a real diagnostic challenge: a normal chest radiograph and nonspecific symptoms do not allow us to exclude this persistent infectious disease. International Scientific Literature, Inc. 2015-04-24 /pmc/articles/PMC4423172/ /pubmed/25907152 http://dx.doi.org/10.12659/AJCR.892546 Text en © Am J Case Rep, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Articles
Manca, Sandra
Fois, Alessandro Giuseppe
Santoru, Luigi
Trisolini, Rocco
Polo, Maria Francesca
Ostera, Salvatore
Patelli, Marco
Pirina, Pietro
Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title_full Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title_fullStr Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title_full_unstemmed Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title_short Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness
title_sort unusual clinical presentation of thoracic tuberculosis: the need for a better knowledge of illness
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423172/
https://www.ncbi.nlm.nih.gov/pubmed/25907152
http://dx.doi.org/10.12659/AJCR.892546
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