Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

Cell-surface Fcγ receptors mediate innate and adaptive immune responses. Human Fcγ receptor I (hFcγRI) binds IgGs with high affinity and is the only Fcγ receptor that can effectively capture monomeric IgGs. However, the molecular basis of hFcγRI's interaction with Fc has not been determined, li...

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Detalles Bibliográficos
Autores principales: Kiyoshi, Masato, Caaveiro, Jose M.M., Kawai, Takeaki, Tashiro, Shinya, Ide, Teruhiko, Asaoka, Yoshiharu, Hatayama, Kouta, Tsumoto, Kouhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423232/
https://www.ncbi.nlm.nih.gov/pubmed/25925696
http://dx.doi.org/10.1038/ncomms7866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423232/
https://www.ncbi.nlm.nih.gov/pubmed/25925696
http://dx.doi.org/10.1038/ncomms7866

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