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Nasopharyngeal angiofibroma: Our experience and literature review

Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Juvenile nasopharyngeal angiofibroma originates...

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Autores principales: Martins, Mariane Barreto Brandão, de Lima, Francis Vinicius Fontes, Mendonça, Carlos Alberto, de Jesus, Eduardo Passos Fiel, Santos, Arlete Cristina Granizo, Barreto, Valéria Maria Prado, Santos, Ronaldo Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Publicações Ltda 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423317/
https://www.ncbi.nlm.nih.gov/pubmed/25991988
http://dx.doi.org/10.7162/S1809-97772013000100003
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author Martins, Mariane Barreto Brandão
de Lima, Francis Vinicius Fontes
Mendonça, Carlos Alberto
de Jesus, Eduardo Passos Fiel
Santos, Arlete Cristina Granizo
Barreto, Valéria Maria Prado
Santos, Ronaldo Carvalho
author_facet Martins, Mariane Barreto Brandão
de Lima, Francis Vinicius Fontes
Mendonça, Carlos Alberto
de Jesus, Eduardo Passos Fiel
Santos, Arlete Cristina Granizo
Barreto, Valéria Maria Prado
Santos, Ronaldo Carvalho
author_sort Martins, Mariane Barreto Brandão
collection PubMed
description Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. Objective: To retrospectively describe our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma. Scientific drawing: Retrospective, descriptive study conducted after approval from the Ethics Committee of the Federal University of Sergipe (protocol 0114.0.107.000 -11). Methods: We analyzed findings in 20 patients who underwent surgery between 2004 and 2011. Factors analyzed include patient age and gender, symptoms, stages, treatment, length of surgery, intraoperatory bleeding, postoperative need for nasal tampons, hospitalization time, complications, and tumor recurrence. Results: Patients were aged 10–29 years. All patients were treated surgically, including 17 who underwent endoscopic surgery. The mean operation time was 120 min, and the mean bleeding volume was 300 mL. Seventeen patients required clamping of the external carotids and tumor embolization. Conclusion: Endoscopic surgery alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages.
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spelling pubmed-44233172015-05-19 Nasopharyngeal angiofibroma: Our experience and literature review Martins, Mariane Barreto Brandão de Lima, Francis Vinicius Fontes Mendonça, Carlos Alberto de Jesus, Eduardo Passos Fiel Santos, Arlete Cristina Granizo Barreto, Valéria Maria Prado Santos, Ronaldo Carvalho Int Arch Otorhinolaryngol Article Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. Objective: To retrospectively describe our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma. Scientific drawing: Retrospective, descriptive study conducted after approval from the Ethics Committee of the Federal University of Sergipe (protocol 0114.0.107.000 -11). Methods: We analyzed findings in 20 patients who underwent surgery between 2004 and 2011. Factors analyzed include patient age and gender, symptoms, stages, treatment, length of surgery, intraoperatory bleeding, postoperative need for nasal tampons, hospitalization time, complications, and tumor recurrence. Results: Patients were aged 10–29 years. All patients were treated surgically, including 17 who underwent endoscopic surgery. The mean operation time was 120 min, and the mean bleeding volume was 300 mL. Seventeen patients required clamping of the external carotids and tumor embolization. Conclusion: Endoscopic surgery alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages. Thieme Publicações Ltda 2013-01 /pmc/articles/PMC4423317/ /pubmed/25991988 http://dx.doi.org/10.7162/S1809-97772013000100003 Text en © Thieme Medical Publishers
spellingShingle Article
Martins, Mariane Barreto Brandão
de Lima, Francis Vinicius Fontes
Mendonça, Carlos Alberto
de Jesus, Eduardo Passos Fiel
Santos, Arlete Cristina Granizo
Barreto, Valéria Maria Prado
Santos, Ronaldo Carvalho
Nasopharyngeal angiofibroma: Our experience and literature review
title Nasopharyngeal angiofibroma: Our experience and literature review
title_full Nasopharyngeal angiofibroma: Our experience and literature review
title_fullStr Nasopharyngeal angiofibroma: Our experience and literature review
title_full_unstemmed Nasopharyngeal angiofibroma: Our experience and literature review
title_short Nasopharyngeal angiofibroma: Our experience and literature review
title_sort nasopharyngeal angiofibroma: our experience and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423317/
https://www.ncbi.nlm.nih.gov/pubmed/25991988
http://dx.doi.org/10.7162/S1809-97772013000100003
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