A Case of mild idiopathic adulthood ductopenia and brief review of literature

Mild idiopathic adulthood ductopenia (IAD) is a rare cholestatic disease of unknown cause and characterized by interlobular bile duct loss in less than 50% of the portal tracts. We describe the case of a middLe-aged male who presented with persistent elevation of transaminases and alkaline phosphata...

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Detalles Bibliográficos
Autores principales: Kaung, Aung, Sundaram, Vinay, Dhall, Deepti, Tran, Tram T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423457/
https://www.ncbi.nlm.nih.gov/pubmed/25030019
http://dx.doi.org/10.1093/gastro/gou048
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author Kaung, Aung
Sundaram, Vinay
Dhall, Deepti
Tran, Tram T.
author_facet Kaung, Aung
Sundaram, Vinay
Dhall, Deepti
Tran, Tram T.
author_sort Kaung, Aung
collection PubMed
description Mild idiopathic adulthood ductopenia (IAD) is a rare cholestatic disease of unknown cause and characterized by interlobular bile duct loss in less than 50% of the portal tracts. We describe the case of a middLe-aged male who presented with persistent elevation of transaminases and alkaline phosphatase. He had a normal biliary tree on endoscopic retrograde cholangiopathy and negative anti-mitochondrial antibody. His liver biopsy specimen showed chronic biliary disease, duct loss in 4 out of 15 portal tracts and prominent cholestasis. Based on the work-up, he likely had mild IAD. Liver transplantation would be necessary if his disease becomes progressive.
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spelling pubmed-44234572015-05-13 A Case of mild idiopathic adulthood ductopenia and brief review of literature Kaung, Aung Sundaram, Vinay Dhall, Deepti Tran, Tram T. Gastroenterol Rep (Oxf) Case Reports Mild idiopathic adulthood ductopenia (IAD) is a rare cholestatic disease of unknown cause and characterized by interlobular bile duct loss in less than 50% of the portal tracts. We describe the case of a middLe-aged male who presented with persistent elevation of transaminases and alkaline phosphatase. He had a normal biliary tree on endoscopic retrograde cholangiopathy and negative anti-mitochondrial antibody. His liver biopsy specimen showed chronic biliary disease, duct loss in 4 out of 15 portal tracts and prominent cholestasis. Based on the work-up, he likely had mild IAD. Liver transplantation would be necessary if his disease becomes progressive. Oxford University Press 2015-05 2014-07-16 /pmc/articles/PMC4423457/ /pubmed/25030019 http://dx.doi.org/10.1093/gastro/gou048 Text en © The Author(s) 2014. Published by Oxford University Press and the Digestive Science Publishing Co. Limited. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kaung, Aung
Sundaram, Vinay
Dhall, Deepti
Tran, Tram T.
A Case of mild idiopathic adulthood ductopenia and brief review of literature
title A Case of mild idiopathic adulthood ductopenia and brief review of literature
title_full A Case of mild idiopathic adulthood ductopenia and brief review of literature
title_fullStr A Case of mild idiopathic adulthood ductopenia and brief review of literature
title_full_unstemmed A Case of mild idiopathic adulthood ductopenia and brief review of literature
title_short A Case of mild idiopathic adulthood ductopenia and brief review of literature
title_sort case of mild idiopathic adulthood ductopenia and brief review of literature
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423457/
https://www.ncbi.nlm.nih.gov/pubmed/25030019
http://dx.doi.org/10.1093/gastro/gou048
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