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uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies

Urokinase plasminogen activator (uPA) is an extracellular matrix-degrading protease involved in cancer invasion and metastasis, interacting with plasminogen activator inhibitor-1 (PAI-1), which was originally identified as a blood-derived endogenous fast-acting inhibitor of uPA. At concentrations fo...

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Detalles Bibliográficos
Autores principales:	Duffy, Michael J, McGowan, Patricia M, Harbeck, Nadia, Thomssen, Christoph, Schmitt, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423643/ https://www.ncbi.nlm.nih.gov/pubmed/25677449 http://dx.doi.org/10.1186/s13058-014-0428-4

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