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Heterozygous genome assembly via binary classification of homologous sequence
BACKGROUND: Genome assemblers to date have predominantly targeted haploid reference reconstruction from homozygous data. When applied to diploid genome assembly, these assemblers perform poorly, owing to the violation of assumptions during both the contigging and scaffolding phases. Effective tools...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423727/ https://www.ncbi.nlm.nih.gov/pubmed/25952609 http://dx.doi.org/10.1186/1471-2105-16-S7-S5 |