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Drak2 Does Not Regulate TGF-β Signaling in T Cells
Drak2 is a serine/threonine kinase expressed highest in T cells and B cells. Drak2(-/-) mice are resistant to autoimmunity in mouse models of type 1 diabetes and multiple sclerosis. Resistance to these diseases occurs, in part, because Drak2 is required for the survival of autoreactive T cells that...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423867/ https://www.ncbi.nlm.nih.gov/pubmed/25951457 http://dx.doi.org/10.1371/journal.pone.0123650 |