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Drak2 Does Not Regulate TGF-β Signaling in T Cells

Drak2 is a serine/threonine kinase expressed highest in T cells and B cells. Drak2(-/-) mice are resistant to autoimmunity in mouse models of type 1 diabetes and multiple sclerosis. Resistance to these diseases occurs, in part, because Drak2 is required for the survival of autoreactive T cells that...

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Detalles Bibliográficos
Autores principales:	Harris, Tarsha L., McGargill, Maureen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423867/ https://www.ncbi.nlm.nih.gov/pubmed/25951457 http://dx.doi.org/10.1371/journal.pone.0123650

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