Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light

Sleep and/or circadian rhythm disruption (SCRD) is seen in up to 80% of schizophrenia patients. The co-morbidity of schizophrenia and SCRD may in part stem from dysfunction in common brain mechanisms, which include the glutamate system, and in particular, the group II metabotropic glutamate receptor...

Descripción completa

Detalles Bibliográficos
Autores principales: Pritchett, David, Jagannath, Aarti, Brown, Laurence A., Tam, Shu K. E., Hasan, Sibah, Gatti, Silvia, Harrison, Paul J., Bannerman, David M., Foster, Russell G., Peirson, Stuart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423919/
https://www.ncbi.nlm.nih.gov/pubmed/25950516
http://dx.doi.org/10.1371/journal.pone.0125523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423919/
https://www.ncbi.nlm.nih.gov/pubmed/25950516
http://dx.doi.org/10.1371/journal.pone.0125523

Ejemplares similares