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The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
Aberrant glycosylation occurs in the majority of human cancers and changes in mucin-type O-glycosylation are key events that play a role in the induction of invasion and metastases. These changes generate novel cancer-specific glyco-antigens that can interact with cells of the immune system through...
Autores principales: | Beatson, Richard, Maurstad, Gjertrud, Picco, Gianfranco, Arulappu, Appitha, Coleman, Julia, Wandell, Hans H., Clausen, Henrik, Mandel, Ulla, Taylor-Papadimitriou, Joyce, Sletmoen, Marit, Burchell, Joy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423978/ https://www.ncbi.nlm.nih.gov/pubmed/25951175 http://dx.doi.org/10.1371/journal.pone.0125994 |
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