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Palmitoylethanolamide Treatment Reduces Blood Pressure in Spontaneously Hypertensive Rats: Involvement of Cytochrome P450-Derived Eicosanoids and Renin Angiotensin System
Palmitoylethanolamide (PEA), a peroxisome proliferator-activated receptor-α agonist, has been demonstrated to reduce blood pressure and kidney damage secondary to hypertension in spontaneously hypertensive rat (SHR). Currently, no information is available concerning the putative effect of PEA on mod...
Autores principales: | Mattace Raso, Giuseppina, Pirozzi, Claudio, d'Emmanuele di Villa Bianca, Roberta, Simeoli, Raffaele, Santoro, Anna, Lama, Adriano, Di Guida, Francesca, Russo, Roberto, De Caro, Carmen, Sorrentino, Raffaella, Calignano, Antonio, Meli, Rosaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423982/ https://www.ncbi.nlm.nih.gov/pubmed/25951330 http://dx.doi.org/10.1371/journal.pone.0123602 |
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