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PRESTO-TANGO: an open-source resource for interrogation of the druggable human GPCR-ome
G protein-coupled receptors (GPCRs) are essential mediators of cellular signaling and important targets of drug action. Of the approximately 350 non-olfactory human GPCRs, more than 100 are still considered “orphans” as their endogenous ligand(s) remain unknown. Here, we describe a unique open-sourc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424118/ https://www.ncbi.nlm.nih.gov/pubmed/25895059 http://dx.doi.org/10.1038/nsmb.3014 |