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PTEN–Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injury

PTEN is a multifunctional phosphatase that regulates immune responses through a PI3K/Akt signaling cascade. HMGB1 plays an important role in the initiation of innate immune responses to induce acute lung injury (ALI). This study was designed to investigate the role of PTEN/Foxo1 signaling in the reg...

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Detalles Bibliográficos
Autores principales:	Zhou, Min, Zhang, Yadi, Chen, Xulin, Zhu, Jianjun, Du, Min, Zhou, Liang, Zhang, Ling, Wang, Wei, Sun, Gengyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424276/ https://www.ncbi.nlm.nih.gov/pubmed/25759027 http://dx.doi.org/10.1007/s12026-015-8639-z

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