Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis

BACKGROUND: In an adaptive clinical trial (ACT), key trial characteristics may be altered during the course of the trial according to predefined rules in response to information that accumulates within the trial itself. In addition to having distinguishing scientific features, adaptive trials also m...

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Detalles Bibliográficos
Autores principales: Legocki, Laurie J, Meurer, William J, Frederiksen, Shirley, Lewis, Roger J, Durkalski, Valerie L, Berry, Donald A, Barsan, William G, Fetters, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424427/
https://www.ncbi.nlm.nih.gov/pubmed/25933921
http://dx.doi.org/10.1186/s12910-015-0022-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424427/
https://www.ncbi.nlm.nih.gov/pubmed/25933921
http://dx.doi.org/10.1186/s12910-015-0022-z

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