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Carriage burden, multiple colonization and antibiotic pressure promote emergence of resistant vaccine escape pneumococci
Pneumococcal conjugate vaccines target the limited subset of the more than 90 known serotypes of Streptococcus pneumoniae responsible for the greatest burden of pneumococcal disease and antibiotic resistance. Following the introduction of these vaccines, serotypes not targeted were able to expand an...
Autores principales: | Mitchell, Patrick K., Lipsitch, Marc, Hanage, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424439/ https://www.ncbi.nlm.nih.gov/pubmed/25918447 http://dx.doi.org/10.1098/rstb.2014.0342 |
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