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Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype

BACKGROUND: The term CpG island methylator phenotype (CIMP) has been used to describe widespread DNA hypermethylation at CpG-rich genomic regions affecting clinically distinct subsets of cancer patients. Even though there have been numerous studies of CIMP in individual cancer types, a uniform analy...

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Detalles Bibliográficos
Autores principales:	Sánchez-Vega, Francisco, Gotea, Valer, Margolin, Gennady, Elnitski, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424513/ https://www.ncbi.nlm.nih.gov/pubmed/25960768 http://dx.doi.org/10.1186/s13072-015-0007-7

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