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CD11b is protective in complement-mediated immune complex glomerulonephritis
In chronic serum sickness, glomerular immune complexes form, yet C57BL/6 mice do not develop glomerulonephritis unless complement factor H (CfH) is absent, indicating the relevance of complement regulation. Complement receptor 3 (CD11b) and Fcγ receptors on leukocytes, and CfH on platelets, can bind...
Autores principales: | Alexander, Jessy J, Chaves, Lee D, Chang, Anthony, Jacob, Alexander, Ritchie, Maria, Quigg, Richard J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424815/ https://www.ncbi.nlm.nih.gov/pubmed/25565310 http://dx.doi.org/10.1038/ki.2014.373 |
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