Application of Single Molecule Fluorescence Microscopy to Characterize the Penetration of a Large Amphiphilic Molecule in the Stratum Corneum of Human Skin

We report here on the application of laser-based single molecule total internal reflection fluorescence microscopy (TIRFM) to study the penetration of molecules through the skin. Penetration of topically applied drug molecules is often observed to be limited by the size of the respective drug. Howev...

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Detalles Bibliográficos
Autores principales: Volz, Pierre, Boreham, Alexander, Wolf, Alexander, Kim, Tai-Yang, Balke, Jens, Frombach, Janna, Hadam, Sabrina, Afraz, Zahra, Rancan, Fiorenza, Blume-Peytavi, Ulrike, Vogt, Annika, Alexiev, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424999/
https://www.ncbi.nlm.nih.gov/pubmed/25826528
http://dx.doi.org/10.3390/ijms16046960

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