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Autophagy Induction by Silibinin Positively Contributes to Its Anti-Metastatic Capacity via AMPK/mTOR Pathway in Renal Cell Carcinoma

Silibinin, a dietary cancer chemopreventive flavonoid from the seeds of milk thistle, has been reported to exhibit anti-metastatic effects on renal cell carcinoma (RCC), but the mechanism underlying this phenomenon is not fully understood. The present study aimed at examining the potential role of a...

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Detalles Bibliográficos
Autores principales: Li, Feng, Ma, Zhenkun, Guan, Zhenfeng, Chen, Yule, Wu, Kaijie, Guo, Peng, Wang, Xinyang, He, Dalin, Zeng, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425089/
https://www.ncbi.nlm.nih.gov/pubmed/25884331
http://dx.doi.org/10.3390/ijms16048415