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Autophagy Induction by Silibinin Positively Contributes to Its Anti-Metastatic Capacity via AMPK/mTOR Pathway in Renal Cell Carcinoma
Silibinin, a dietary cancer chemopreventive flavonoid from the seeds of milk thistle, has been reported to exhibit anti-metastatic effects on renal cell carcinoma (RCC), but the mechanism underlying this phenomenon is not fully understood. The present study aimed at examining the potential role of a...
Autores principales: | Li, Feng, Ma, Zhenkun, Guan, Zhenfeng, Chen, Yule, Wu, Kaijie, Guo, Peng, Wang, Xinyang, He, Dalin, Zeng, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425089/ https://www.ncbi.nlm.nih.gov/pubmed/25884331 http://dx.doi.org/10.3390/ijms16048415 |
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