The mechanism of CCN1-enhanced retinal neovascularization in oxygen-induced retinopathy through PI3K/Akt–VEGF signaling pathway

BACKGROUND: CCN1 (also called Cyr 61) is an extracellular matrix signaling molecule that has been implicated in neovascularization through its interactions with several endothelial integrin receptors. The roles of vascular endothelial growth factor (VEGF) in angiogenesis are well described. The aim...

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Detalles Bibliográficos
Autores principales: Di, Yu, Zhang, Yiou, Yang, Hongwei, Wang, Aiyuan, Chen, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425238/
https://www.ncbi.nlm.nih.gov/pubmed/25995618
http://dx.doi.org/10.2147/DDDT.S79782

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