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Hydroxypropyl-β-cyclodextrin functionalized calcium carbonate microparticles as a potential carrier for enhancing oral delivery of water-insoluble drugs

The objective of the present study was to demonstrate that a novel hydroxypropyl-β-cyclodextrin functionalized calcium carbonate (HP-β-CD/CC) based amorphous solid dispersion (ASD) can be used to increase the solubility and oral bioavailability of water-insoluble drugs. Irbesartan (IRB) was selected...

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Detalles Bibliográficos
Autores principales:	Zhang, Lihua, Zhu, Wufu, Lin, Qisi, Han, Jin, Jiang, Liqun, Zhang, Yanzhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425320/ https://www.ncbi.nlm.nih.gov/pubmed/25995635 http://dx.doi.org/10.2147/IJN.S78814

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