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Epigallocatechin 3-Gallate Ameliorates Bile Duct Ligation Induced Liver Injury in Mice by Modulation of Mitochondrial Oxidative Stress and Inflammation
Cholestatic liver fibrosis was achieved by bile duct ligation (BDL) in mice. Liver injury associated with BDL for 15 days included significant reactive oxygen/nitrogen species generation, liver inflammation, cell death and fibrosis. Administration of Epigallocatechin 3-Gallate (EGCG) in animals redu...
Autores principales: | Shen, Kezhen, Feng, Xiaowen, Su, Rong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425400/ https://www.ncbi.nlm.nih.gov/pubmed/25955525 http://dx.doi.org/10.1371/journal.pone.0126278 |
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