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Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells

PURPOSE: We recently found that the tetraspanin family member, CD82, which is aberrantly expressed in chemotherapy-resistant CD34(+)/CD38(−) acute myelogenous leukemia (AML) cells, negatively regulates matrix metalloproteinase 9, and plays an important role in enabling CD34(+)/CD38(−) AML cells to a...

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Detalles Bibliográficos
Autores principales: Nishioka, Chie, Ikezoe, Takayuki, Yang, Jing, Yokoyama, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425466/
https://www.ncbi.nlm.nih.gov/pubmed/25955299
http://dx.doi.org/10.1371/journal.pone.0125017

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