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pGlcNAc Nanofiber Treatment of Cutaneous Wounds Stimulate Increased Tensile Strength and Reduced Scarring via Activation of Akt1

Treatment of cutaneous wounds with poly-N-acetyl-glucosamine containing nanofibers (pGlcNAc), a novel polysaccharide material derived from a marine diatom, results in increased wound closure, antibacterial activities and innate immune responses. We have shown that Akt1 plays a central role in the re...

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Detalles Bibliográficos
Autores principales: Lindner, Haley Buff, Felmly, Lloyd McPherson, Demcheva, Marina, Seth, Arun, Norris, Russell, Bradshaw, Amy D., Vournakis, John, Muise-Helmericks, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425470/
https://www.ncbi.nlm.nih.gov/pubmed/25955155
http://dx.doi.org/10.1371/journal.pone.0127876