Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN

BACKGROUND: Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, canine SNP microarrays were used to study 117 canine mammary tumours from 69 d...

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Detalles Bibliográficos
Autores principales: Borge, Kaja S., Nord, Silje, Van Loo, Peter, Lingjærde, Ole C., Gunnes, Gjermund, Alnæs, Grethe I. G., Solvang, Hiroko K., Lüders, Torben, Kristensen, Vessela N., Børresen-Dale, Anne-Lise, Lingaas, Frode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425491/
https://www.ncbi.nlm.nih.gov/pubmed/25955013
http://dx.doi.org/10.1371/journal.pone.0126371

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