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Targeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic Hypogonadism
Mice lacking ALK activity have previously been reported to exhibit subtle behavioral phenotypes. In this study of ALK of loss of function mice we present data supporting a role for ALK in hypogonadotropic hypogonadism in male mice. We observed lower level of serum testosterone at P40 in ALK knock-ou...
Autores principales: | Witek, Barbara, El Wakil, Abeer, Nord, Christoffer, Ahlgren, Ulf, Eriksson, Maria, Vernersson-Lindahl, Emma, Helland, Åslaug, Alexeyev, Oleg A., Hallberg, Bengt, Palmer, Ruth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425494/ https://www.ncbi.nlm.nih.gov/pubmed/25955180 http://dx.doi.org/10.1371/journal.pone.0123542 |
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