Molecular Heterogeneity in a Patient-Derived Glioblastoma Xenoline Is Regulated by Different Cancer Stem Cell Populations

Malignant glioblastoma (GBM) is a highly aggressive brain tumor with a dismal prognosis and limited therapeutic options. Genomic profiling of GBM samples has identified four molecular subtypes (Proneural, Neural, Classical and Mesenchymal), which may arise from different glioblastoma stem-like cell...

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Detalles Bibliográficos
Autores principales: Garner, Jo Meagan, Ellison, David W., Finkelstein, David, Ganguly, Debolina, Du, Ziyun, Sims, Michelle, Yang, Chuan He, Interiano, Rodrigo B., Davidoff, Andrew M., Pfeffer, Lawrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425556/
https://www.ncbi.nlm.nih.gov/pubmed/25955030
http://dx.doi.org/10.1371/journal.pone.0125838

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