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Genome-wide association study of kidney function decline in individuals of European descent

Genome wide association studies (GWAS) have identified multiple loci associated with cross-sectional eGFR, but a systematic genetic analysis of kidney function decline over time is missing. Here we conducted a GWAS meta-analysis among 63,558 participants of European descent, initially from 16 cohort...

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Detalles Bibliográficos
Autores principales: Gorski, Mathias, Tin, Adrienne, Garnaas, Maija, McMahon, Gearoid M., Chu, Audrey Y., Tayo, Bamidele O., Pattaro, Cristian, Teumer, Alexander, Chasman, Daniel I., Chalmers, John, Hamet, Pavel, Tremblay, Johanne, Woodward, Marc, Aspelund, Thor, Eiriksdottir, Gudny, Gudnason, Vilmundur, Harris, Tammara B., Launer, Lenore J., Smith, Albert V., Mitchell, Braxton D., O'Connell, Jeffrey R., Shuldiner, Alan R., Coresh, Josef, Li, Man, Freudenberger, Paul, Hofer, Edith, Schmidt, Helena, Schmidt, Reinhold, Holliday, Elizabeth G., Mitchell, Paul, Wang, Jie Jin, de Boer, Ian H., Li, Guo, Siscovick, David S., Kutalik, Zoltan, Corre, Tanguy, Vollenweider, Peter, Waeber, Gérard, Gupta, Jayanta, Kanetsky, Peter A., Hwang, Shih-Jen, Olden, Matthias, Yang, Qiong, de Andrade, Mariza, Atkinson, Elizabeth J., Kardia, Sharon L.R., Turner, Stephen T., Stafford, Jeanette M., Ding, Jingzhong, Liu, Yongmei, Barlassina, Cristina, Cusi, Daniele, Salvi, Erika, Staessen, Jan A, Ridker, Paul M, Grallert, Harald, Meisinger, Christa, Müller-Nurasyid, Martina, Krämer, Bernhard K., Kramer, Holly, Rosas, Sylvia E., Nolte, Ilja M., Penninx, Brenda W., Snieder, Harold, Del Greco, Fabiola, Franke, Andre, Nöthlings, Ute, Lieb, Wolfgang, Bakker, Stephan J.L., Gansevoort, Ron T., van der Harst, Pim, Dehghan, Abbas, Franco, Oscar H., Hofman, Albert, Rivadeneira, Fernando, Sedaghat, Sanaz, Uitterlinden, André G., Coassin, Stefan, Haun, Margot, Kollerits, Barbara, Kronenberg, Florian, Paulweber, Bernhard, Aumann, Nicole, Endlich, Karlhans, Pietzner, Mike, Völker, Uwe, Rettig, Rainer, Chouraki, Vincent, Helmer, Catherine, Lambert, Jean-Charles, Metzger, Marie, Stengel, Benedicte, Lehtimäki, Terho, Lyytikäinen, Leo-Pekka, Raitakari, Olli, Johnson, Andrew, Parsa, Afshin, Bochud, Murielle, Heid, Iris M., Goessling, Wolfram, Köttgen, Anna, Kao, H. Linda, Fox, Caroline S., Böger, Carsten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425568/
https://www.ncbi.nlm.nih.gov/pubmed/25493955
http://dx.doi.org/10.1038/ki.2014.361