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Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin

Erythropoietin (EPO) is critical for red blood cell production and is also an effective neuroprotective agent. However, it may also contribute to pathological angiogenesis. Here we investigate the angiogenic potential of EPO and a mutant form with attenuated erythropoietic activity, EPO-R76E, on pri...

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Detalles Bibliográficos
Autores principales: de Lucas Cerrillo, Ana, Bond, Wesley S., Rex, Tonia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425572/
https://www.ncbi.nlm.nih.gov/pubmed/25716531
http://dx.doi.org/10.1038/gt.2015.12

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