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p47phox contributes to albuminuria and kidney fibrosis in mice
Reactive oxygen species (ROS) play an important pathogenic role in the development of many diseases, including kidney disease. Major ROS generators in the glomerulus of the kidney are the p47phox-containing NAPDH oxidases NOX1 and NOX2. The cytosolic p47phox subunit is a key regulator of the assembl...
Autores principales: | Wang, Hongtao, Chen, Xiwu, Su, Yan, Paueksakon, Paisit, Hu, Wen, Zhang, Ming-Zhi, Harris, Raymond C., Blackwell, Timothy S., Zent, Roy, Pozzi, Ambra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425591/ https://www.ncbi.nlm.nih.gov/pubmed/25565313 http://dx.doi.org/10.1038/ki.2014.386 |
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