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Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
Peroxisome-proliferator activated receptor-γ (PPARγ) is a nuclear hormone receptor that forms a heterodimeric complex with retinoid X receptor-α (RXRα) to regulate transcription of genes involved in fatty acid storage and glucose metabolism. PPARγ is a target for pharmaceutical intervention in type...
Autores principales: | Lemkul, Justin A., Lewis, Stephanie N., Bassaganya-Riera, Josep, Bevan, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425662/ https://www.ncbi.nlm.nih.gov/pubmed/25954810 http://dx.doi.org/10.1371/journal.pone.0123984 |
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