Investigating interactions between phentermine, dexfenfluramine, and 5-HT(2C) agonists, on food intake in the rat

RATIONALE: Synergistic or supra-additive interactions between the anorectics (dex)fenfluramine and phentermine have been reported previously in the rat and in the clinic. Studies with 5-HT(2C) antagonists and 5-HT(2C) knockouts have demonstrated dexfenfluramine hypophagia in the rodent to be mediate...

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Detalles Bibliográficos
Autores principales: Grottick, Andrew J., Whelan, Kevin, Sanabria, Erin K., Behan, Dominic P., Morgan, Michael, Sage, Carleton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425807/
https://www.ncbi.nlm.nih.gov/pubmed/25524140
http://dx.doi.org/10.1007/s00213-014-3829-2

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