Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells

INTRODUCTION: Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has been found to have therapeutic potential for treating cancers associated with impaired DNA repair capabilities, particularly those with deficiencies in the homologous recombination repair (HRR) pathway. Histone deacetylases...

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Detalles Bibliográficos
Autores principales: Min, Ahrum, Im, Seock-Ah, Kim, Debora Keunyoung, Song, Sang-Hyun, Kim, Hee-Jun, Lee, Kyung-Hun, Kim, Tae-Yong, Han, Sae-Won, Oh, Do-Youn, Kim, Tae-You, O’Connor, Mark J, Bang, Yung-Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425881/
https://www.ncbi.nlm.nih.gov/pubmed/25888415
http://dx.doi.org/10.1186/s13058-015-0534-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425881/
https://www.ncbi.nlm.nih.gov/pubmed/25888415
http://dx.doi.org/10.1186/s13058-015-0534-y

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