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The left ventricle in aortic stenosis – imaging assessment and clinical implications
Aortic stenosis has an increasing prevalence in the context of aging population. In these patients non-invasive imaging allows not only the grading of valve stenosis severity, but also the assessment of left ventricular function. These two goals play a key role in clinical decision-making. Although...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425891/ https://www.ncbi.nlm.nih.gov/pubmed/25928763 http://dx.doi.org/10.1186/s12947-015-0017-4 |
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author | Călin, Andreea Roşca, Monica Beladan, Carmen Cristiana Enache, Roxana Mateescu, Anca Doina Ginghină, Carmen Popescu, Bogdan Alexandru |
author_facet | Călin, Andreea Roşca, Monica Beladan, Carmen Cristiana Enache, Roxana Mateescu, Anca Doina Ginghină, Carmen Popescu, Bogdan Alexandru |
author_sort | Călin, Andreea |
collection | PubMed |
description | Aortic stenosis has an increasing prevalence in the context of aging population. In these patients non-invasive imaging allows not only the grading of valve stenosis severity, but also the assessment of left ventricular function. These two goals play a key role in clinical decision-making. Although left ventricular ejection fraction is currently the only left ventricular function parameter that guides intervention, current imaging techniques are able to detect early changes in LV structure and function even in asymptomatic patients with significant aortic stenosis and preserved ejection fraction. Moreover, new imaging parameters emerged as predictors of disease progression in patients with aortic stenosis. Although proper standardization and confirmatory data from large prospective studies are needed, these novel parameters have the potential of becoming useful tools in guiding intervention in asymptomatic patients with aortic stenosis and stratify risk in symptomatic patients undergoing aortic valve replacement. This review focuses on the mechanisms of transition from compensatory left ventricular hypertrophy to left ventricular dysfunction and heart failure in aortic stenosis and the role of non-invasive imaging assessment of the left ventricular geometry and function in these patients. |
format | Online Article Text |
id | pubmed-4425891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44258912015-05-10 The left ventricle in aortic stenosis – imaging assessment and clinical implications Călin, Andreea Roşca, Monica Beladan, Carmen Cristiana Enache, Roxana Mateescu, Anca Doina Ginghină, Carmen Popescu, Bogdan Alexandru Cardiovasc Ultrasound Review Aortic stenosis has an increasing prevalence in the context of aging population. In these patients non-invasive imaging allows not only the grading of valve stenosis severity, but also the assessment of left ventricular function. These two goals play a key role in clinical decision-making. Although left ventricular ejection fraction is currently the only left ventricular function parameter that guides intervention, current imaging techniques are able to detect early changes in LV structure and function even in asymptomatic patients with significant aortic stenosis and preserved ejection fraction. Moreover, new imaging parameters emerged as predictors of disease progression in patients with aortic stenosis. Although proper standardization and confirmatory data from large prospective studies are needed, these novel parameters have the potential of becoming useful tools in guiding intervention in asymptomatic patients with aortic stenosis and stratify risk in symptomatic patients undergoing aortic valve replacement. This review focuses on the mechanisms of transition from compensatory left ventricular hypertrophy to left ventricular dysfunction and heart failure in aortic stenosis and the role of non-invasive imaging assessment of the left ventricular geometry and function in these patients. BioMed Central 2015-04-29 /pmc/articles/PMC4425891/ /pubmed/25928763 http://dx.doi.org/10.1186/s12947-015-0017-4 Text en © Calin et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Călin, Andreea Roşca, Monica Beladan, Carmen Cristiana Enache, Roxana Mateescu, Anca Doina Ginghină, Carmen Popescu, Bogdan Alexandru The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title | The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title_full | The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title_fullStr | The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title_full_unstemmed | The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title_short | The left ventricle in aortic stenosis – imaging assessment and clinical implications |
title_sort | left ventricle in aortic stenosis – imaging assessment and clinical implications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425891/ https://www.ncbi.nlm.nih.gov/pubmed/25928763 http://dx.doi.org/10.1186/s12947-015-0017-4 |
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