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Increase in the titer of lentiviral vectors expressing potassium channels by current blockade during viral vector production

BACKGROUND: High titers of lentiviral vectors are required for the efficient transduction of a gene of interest. During preparation of lentiviral the vectors, the protein of interest is inevitably expressed in the viral vector-producing cells. This expression may affect the production of the lentivi...

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Detalles Bibliográficos
Autores principales: Okada, Masayoshi, Andharia, Naaz, Matsuda, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425897/
https://www.ncbi.nlm.nih.gov/pubmed/25940378
http://dx.doi.org/10.1186/s12868-015-0159-1

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