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In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl(−/−)) mice
The lean body weight phenotype of hepatic lipase (HL)–deficient mice (hl(−/−)) suggests that HL is required for normal weight gain, but the underlying mechanisms are unknown. HL plays a unique role in lipoprotein metabolism performing bridging as well as catalytic functions, either of which could pa...
Autores principales: | Chen, Jeffrey, Kaiyala, Karl J, Lam, Jennifer, Agrawal, Nalini, Nguyen, Lisa, Ogimoto, Kayoko, Spencer, Dean, Morton, Gregory J, Schwartz, Michael W, Dichek, Helén L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425970/ https://www.ncbi.nlm.nih.gov/pubmed/25862097 http://dx.doi.org/10.14814/phy2.12365 |
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