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TREM2 is associated with increased risk for Alzheimer’s disease in African Americans

BACKGROUND: TREM2 encodes for triggering receptor expressed on myeloid cells 2 and has rare, coding variants that associate with risk for late-onset Alzheimer’s disease (LOAD) in Caucasians of European and North-American origin. This study evaluated the role of TREM2 in LOAD risk in African-American...

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Detalles Bibliográficos
Autores principales: Jin, Sheng Chih, Carrasquillo, Minerva M, Benitez, Bruno A, Skorupa, Tara, Carrell, David, Patel, Dwani, Lincoln, Sarah, Krishnan, Siddharth, Kachadoorian, Michaela, Reitz, Christiane, Mayeux, Richard, Wingo, Thomas S, Lah, James J, Levey, Allan I, Murrell, Jill, Hendrie, Hugh, Foroud, Tatiana, Graff-Radford, Neill R, Goate, Alison M, Cruchaga, Carlos, Ertekin-Taner, Nilüfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426167/
https://www.ncbi.nlm.nih.gov/pubmed/25886450
http://dx.doi.org/10.1186/s13024-015-0016-9