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Differential Regulation of Antagonistic Pleiotropy in Synthetic and Natural Populations Suggests Its Role in Adaptation

Antagonistic pleiotropy (AP), the ability of a gene to show opposing effects in different phenotypes, has been identified in various life history traits and complex disorders, indicating its fundamental role in balancing fitness over the course of evolution. It is intuitive that natural selection mi...

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Detalles Bibliográficos
Autores principales: Yadav, Anupama, Radhakrishnan, Aparna, Bhanot, Gyan, Sinha, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426359/
https://www.ncbi.nlm.nih.gov/pubmed/25711830
http://dx.doi.org/10.1534/g3.115.017020