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Differential Regulation of Antagonistic Pleiotropy in Synthetic and Natural Populations Suggests Its Role in Adaptation
Antagonistic pleiotropy (AP), the ability of a gene to show opposing effects in different phenotypes, has been identified in various life history traits and complex disorders, indicating its fundamental role in balancing fitness over the course of evolution. It is intuitive that natural selection mi...
Autores principales: | Yadav, Anupama, Radhakrishnan, Aparna, Bhanot, Gyan, Sinha, Himanshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426359/ https://www.ncbi.nlm.nih.gov/pubmed/25711830 http://dx.doi.org/10.1534/g3.115.017020 |
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