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Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice
The non-obese diabetic (NOD) mouse is a polygenic model for type 1 diabetes that is characterized by insulitis, a leukocytic infiltration of the pancreatic islets. During ~35 years since the original inbred strain was developed in Japan, NOD substrains have been established at different laboratories...
Autores principales: | Simecek, Petr, Churchill, Gary A., Yang, Hyuna, Rowe, Lucy B., Herberg, Lieselotte, Serreze, David V., Leiter, Edward H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426365/ https://www.ncbi.nlm.nih.gov/pubmed/25740934 http://dx.doi.org/10.1534/g3.115.017046 |
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