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A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains
The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of sm...
Autores principales: | Andersen, Erik C., Shimko, Tyler C., Crissman, Jonathan R., Ghosh, Rajarshi, Bloom, Joshua S., Seidel, Hannah S., Gerke, Justin P., Kruglyak, Leonid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426375/ https://www.ncbi.nlm.nih.gov/pubmed/25770127 http://dx.doi.org/10.1534/g3.115.017178 |
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