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Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling

BACKGROUND: During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin. We selected specific elastin fragments generated by NE for ant...

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Detalles Bibliográficos
Autores principales:	Kristensen, Jacob H, Karsdal, Morten A, Sand, Jannie MB, Willumsen, Nicholas, Diefenbach, Claudia, Svensson, Birte, Hägglund, Per, Oersnes-Leeming, Diana J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426538/ https://www.ncbi.nlm.nih.gov/pubmed/25935650 http://dx.doi.org/10.1186/s12890-015-0048-5

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