let-7b and let-7c are determinants of intrinsic chemoresistance in renal cell carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is characterized by inherent resistance to chemotherapy. Earlier studies demonstrated that microRNAs (miRNAs) might be involved in the chemosensitivity of cancers. MicroRNA let-7, a putative tumor suppressor, is dysregulated in many cancers. Our study aims to i...

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Detalles Bibliográficos
Autores principales: Peng, Jingtao, Mo, Ren, Ma, Jian, Fan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426556/
https://www.ncbi.nlm.nih.gov/pubmed/25951903
http://dx.doi.org/10.1186/s12957-015-0596-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426556/
https://www.ncbi.nlm.nih.gov/pubmed/25951903
http://dx.doi.org/10.1186/s12957-015-0596-4

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