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let-7b and let-7c are determinants of intrinsic chemoresistance in renal cell carcinoma
BACKGROUND: Renal cell carcinoma (RCC) is characterized by inherent resistance to chemotherapy. Earlier studies demonstrated that microRNAs (miRNAs) might be involved in the chemosensitivity of cancers. MicroRNA let-7, a putative tumor suppressor, is dysregulated in many cancers. Our study aims to i...
Autores principales: | Peng, Jingtao, Mo, Ren, Ma, Jian, Fan, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426556/ https://www.ncbi.nlm.nih.gov/pubmed/25951903 http://dx.doi.org/10.1186/s12957-015-0596-4 |
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