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CART treatment improves memory and synaptic structure in APP/PS1 mice

Major characteristics of Alzheimer’s disease (AD) include deposits of β-amyloid (Aβ) peptide in the brain, loss of synapses, and cognitive dysfunction. Cocaine- and amphetamine-regulated transcript (CART) has recently been reported to attenuate Aβ-induced toxicity. In this study, CART localization i...

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Detalles Bibliográficos
Autores principales: Jin, Jia-li, Liou, Anthony K.F., Shi, Yejie, Yin, Kai-lin, Chen, Ling, Li, Ling-ling, Zhu, Xiao-lei, Qian, Lai, Yang, Rong, Chen, Jun, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426675/
https://www.ncbi.nlm.nih.gov/pubmed/25959573
http://dx.doi.org/10.1038/srep10224