Cargando…
CART treatment improves memory and synaptic structure in APP/PS1 mice
Major characteristics of Alzheimer’s disease (AD) include deposits of β-amyloid (Aβ) peptide in the brain, loss of synapses, and cognitive dysfunction. Cocaine- and amphetamine-regulated transcript (CART) has recently been reported to attenuate Aβ-induced toxicity. In this study, CART localization i...
Autores principales: | Jin, Jia-li, Liou, Anthony K.F., Shi, Yejie, Yin, Kai-lin, Chen, Ling, Li, Ling-ling, Zhu, Xiao-lei, Qian, Lai, Yang, Rong, Chen, Jun, Xu, Yun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426675/ https://www.ncbi.nlm.nih.gov/pubmed/25959573 http://dx.doi.org/10.1038/srep10224 |
Ejemplares similares
-
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β-amyloid metabolism-associated enzymes
por: Jiang, Hui, et al.
Publicado: (2021) -
Excitability and Synaptic Alterations in the Cerebellum of APP/PS1 Mice
por: Hoxha, Eriola, et al.
Publicado: (2012) -
ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice
por: Song, Leigang, et al.
Publicado: (2023) -
Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice
por: Zheng, Ling, et al.
Publicado: (2022) -
Huatuo Zaizao pill ameliorates cognitive impairment of APP/PS1 transgenic mice by improving synaptic plasticity and reducing Aβ deposition
por: Zhang, Jing-Hua, et al.
Publicado: (2018)